Synergism Guide

This "guide" is an amalgamation of the pins in the Synergism discord server and partial guides.

Disclaimer
So, these kind of games are basically the whole reason why the wiki was created in the first place. This is the kind of game which is great, but needs a guide and currently does not have have a neat guide from the start to the end, but instead general advice and guides for short sections of this game. I have not fully played synergism and as mentioned, this will be an amalgamation of the pins on the discord server. So if you are reading this, expect the guide to be shaky at best.

Pre-reincarnation
So, first some general tips:


 * The quarks are for shop upgrades unlocked after reincarnation (think of them as premium currency given very generously.)
 * You unlock offerings on resets based on time, the tier of the reset and other factors. These can be spent on runes which provides a variety of boosts. The Runes scale in cost, so it will be easier to level up a lower levelled rune, and the later runes will have more base cost than the previous runes (speed rune costs less than prism rune at the same level).
 * auto prestige and auto transcend can effectively be ignored.

Once you have transcended (second tier reset) you can do C1x1 straight away. C1-5x1 unlocks their numbered crystal building buyers, x3 unlocks their number crystal building upgrade autobuyer c1x5 and c2x5 unlock multiplier and accelerator autobuyer at the start of a transcend/challenge respectively, and 1000 of each coin building except alchemies which is 666 unlocks their respective autobuyer at the start of a transcension/challenge. Whenever you're stuck, keep doing challenges.